Expression and function of two olfactory-related genes in response to methyl salicylate in the wolf spider Pardosa pseudoannulata (Araneae: Lycosidae)

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  Expression and function of two olfactory-related genes in response to methyl salicylate in the wolf spider Pardosa pseudoannulata (Araneae: Lycosidae) The wolf spider ( Pardosa pseudoannulata ) is common in rice fields. Olfaction is crucial for perceiving chemical information, and our previous research indicated that methyl salicylate (MeSA), a common herbivore-induced plant volatile (HIPV), significantly attracts P. pseudoannulata . However, few studies have examined the functions of spiders' olfactory-related genes and their interactions with HIPVs. This study aimed to identify olfactory-related genes associated with MeSA in P. pseudoannulata . Transcriptome analysis revealed four differentially expressed olfactory-related genes in response to MeSA in P. pseudoannulata . Subsequent molecular docking analysis indicated that MeSA had a strong predicted binding affinity with proteins of two key olfactory-related genes ( PpseNPC2-7 and PpseSNMP2 ). These two genes were cloned, and...

The need for a refined scorpion antivenom for Iran

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The need for a refined scorpion antivenom for Iran

Abstract

Scorpion sting is a medical burden globally but especially frequent hotspots of scorpion biodiversity. In Iran, one of those hotspot countries, many fatalities occur in the South as well as the Southwest and are thought to be caused by Hemiscorpius lepturus. Accordingly, those are used for antivenom production. However, recent surveys revealed that indeed a different species Hemiscorpius acanthocercus is responsible for most accidents in the South, while H. lepturus is primarily causing the fatalities in the Southwest and thus Iranian scorpion antivenom needs to be refined in that respect. Such a refined antivenom would need to cover both species of Hemiscorpius. In response, the Iranian government requested the adjustment of the production line from local antivenom suppliers but until today no action has been taken.


Mahdi Kazemi, S., Kelisani, Z. G., Avella, I., & Lüddecke, T. (2024). The need for a refined scorpion antivenom for Iran. Toxicon, 108033. https://doi.org/10.1016/j.toxicon.2024.108033